Ayomide has worked in healthcare, digital technology and development. He has experience working as a clinician in public and private health facilities that catered to low and middle income earners in Nigeria. He also worked as a consultant on a Global Fund HIV/AIDS project in Lagos State, Nigeria, where he helped health facilities offer standard care and management to people living with HIV/AIDS. He is a partner at The Wellviser Company, owners of www.wellvis.org; a digital health solutions start-up in Lagos, Nigeria.